Effect of smoking on human natural killer cell activity
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چکیده
منابع مشابه
Medullasin enhances human natural killer cell activity.
Medullasin, a new serine protease found in bone marrow cells, increased markedly human natural killer cell activity. Whereas the natural killer cell activity measured immediately after the treatment with medullasin remained almost on the same level as the control, an incubation at 37 degrees C for several hours increased markedly the natural killer cell activity of the lymphocytes treated with ...
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Natural killer (NK) cells are lymphocytes of the innate immune system that secrete cytokines upon activation and mediate the killing of tumor cells and virus-infected cells, especially those that escape the adaptive T cell response caused by the down regulation of MHC-I. The induction of cytotoxicity requires that NK cells contact target cells through adhesion receptors, and initiate activation...
متن کاملHormonal modulation of human natural killer cell activity in vitro.
This study investigates the effect of steroid and polypeptide hormones on human NK cell activity in vitro. Solutions of hormones were incubated with normal peripheral blood cells in a 4 h cytotoxic assay against the NK-sensitive erythromyeloid cell line K562. The steroid hormones oestradiol, progesterone and testosterone did not exhibit a significant effect on K562 lysis at concentrations withi...
متن کامل[Chemiluminescence assay for human natural killer cell activity].
Recently it has been shown that the natural killer (NK)-target cell interaction results in an immediate burst of chemiluminescence. In this paper we investigated to apply chemilumines cence assay for the evaluation of human NK cell activities. Degrees of chemiluminescence were dependent on the concentration of lymphocytes or tar. get cells, but optimal concentrations of lymphocytes and target c...
متن کاملModulation of Natural Killer Cell Activity
Natural killer (NK) cells are a heterogenous subpopulation of peripheral blood lymphocytes (PBL) that have the ability to kill various tumors and tumor cell lines in the absence of prior sensitization. These cells have generated considerable interest and have been implicated in natural resistance to tumors,'-5 resistance to viral infection:-7 transplantation rejection,'** and immunoregulation o...
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ژورنال
عنوان ژورنال: Cancer
سال: 1985
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19851215)56:12<2789::aid-cncr2820561213>3.0.co;2-2